娱网棋牌大厅

  • <strong id="8oimg"></strong>

  • /   Home   /   Newsroom   /   Research News

    New Class of Blue-LED-excitable Second Near-infrared Luminescent Nanoprobes Developed Based on Lanthanide-doped CaS Nanoparticles

    Jun 13, 2019     Email"> PrintText Size

    Lanthanide (Ln3+)-doped luminescent nanoparticles (NPs) with emission in the second near-infrared (NIR-II: 1000-1700 nm) biological window have shown great promise in various bioapplications, but they are currently limited by the low absorption efficiency of Ln3+ due to the parity-forbidden 4f→4f electronic transition. 

    In a study published in Angew. Chem. Int. Ed., a research group led by Prof. CHEN Xueyuan from Fujian Institute of Research on the Structure of Matter (FJIRSM) of the Chinese Academy of Sciences developed a novel strategy for the controlled synthesis of a new class of NIR-II luminescent nanoprobes based on Ln3+ co-doped CaS NPs.  

    Through photoluminescence (PL) and PL decay analyses, researchers comprehensively surveyed the effect of NP size and doping concentration on the optical properties as well as the energy transfer processes in Ce3+ singly doped and Ce3+/Er3+ and Ce3+/Nd3+ co-doped CaS NPs.  

    Besides, through sensitization by the allowed 4f→5d transition of Ce3+, they achieved intense NIR-II luminescence from Er3+ and Nd3+ with quantum yields of 9.3% and 7.7%, respectively, under blue light emitting diode (LED) chip excitation. 

    After surface modification with a layer of amphiphilic phospholipids, these NPs can be stably dispersed in aqueous solution and explored as sensitive NIR-II luminescent nanoprobes for sensitive and selective detection of an important disease biomarker, xanthine, in human serum with a limit of detection (LOD) of 32.0 nM. 

    This study provides a general approach for the development of highly efficient Ln3+-doped NIR-II luminescent nanoprobes through intrinsic antenna sensitization, thereby opening up a new avenue for the exploration of NIR-II luminescent nanoprobes towards versatile bioapplications, such as chip-based point-of-care testing for clinical bioassays.  

     

    Schematic illustration of blue-LED-excitable NIR-II luminescent CaS:Ce3+/Er3+ and CaS:Ce3+/Nd3+ nanoprobes and their application for xanthine detection. (Image by Prof. CHEN’s group) 

    (Editor: LIU Jia)

    Related Articles

    enhanced absorpation; optical waveguide; photoluminescence; electrical properties; organic semiconductor; single crystalline nanorod

    Researchers Improve Photophysical and Electrical Properties of Organic Semiconductor Nanostructure

    May 04, 2016

    Researchers in High Magnetic Field Laboratory, Chinese Academy of Science (CHMFL) in Hefei prepared film and array-arranged single crystalline nanorod (NR) of perylene-3,4,9,10-tetracarboxylic dianhydride (PTCDA) by organic molecular beam deposition me...

    Au;nanoclusters;kernel-atom packing; photoluminescence;structural isomerism;gold;nanoparticle

    Chinese Researchers Develop Structural Isomerism of Gold Nanoparticles

    Mar 13, 2019

    According to new study reported by scientists in Hefei Institutes of Physical Science, fcc-structured gold nanoclusters have stronger photoluminescence than non-fcc structured gold nanoclusters for structural isomerism. Scientists developed a novel ion...

    bismuth;lead-free;nanocrystal;perovskite;photoluminescence

    DICP Scientists Reveal Lead-Free Perovskite Nanocrystals Photophysical Mechanism

    Sep 11, 2017

    Scientists HAN Keli et al. from Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS), synthesized a new lead-free Cs3Bi2Br9 NCs and revealed the photophysical mechanism of it.The results were published in Angew. Chem. In...

    Contact Us

    Copyright ? 2002 - Chinese Academy of Sciences

    Copyright © 2019.娱网棋牌大厅 All rights reserved.m.52kct.cn

    新开棋牌| 老k棋牌| 鼎盛棋牌下载| 棋牌中心APP| 宜宾博雅棋牌下载官网